Metabolic Flexibility, Muscle Mass & Foot Biomechanics for Longevity with Mark Sisson

Photo of Mark Sisson
I'm Dr. Stephanie

My life's passion and mission is blending modern science with ancient wisdom to empower women's health and healing.

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Mark Sisson is the mastermind behind Primal Kitchen, a name you probably recognize from your fridge, and he’s also the founder of the Primal Health Coach Institute. With a New York Times best-selling book, “The Keto Reset Diet,” and the popular health and fitness blog, Mark’s Daily Apple, he’s been a leading figure in the industry for over a decade.

In this episode, Mark and Dr. Stephanie dive deep into the secrets of longevity and what it takes to live a long and healthy life. Mark, who’s 70 years old and looks phenomenal, shares invaluable insights on the foods that impact our health span and lifespan. We discuss foods to embrace and those to avoid, protein intake, and his perspective on maintaining a strong body through exercises, both low and high intensity. Mark’s wisdom extends to biomechanics, particularly the importance of proper foot mechanics for activities like squats and walking, as well as overall well-being. We also explore his innovative venture, Peluva, a five-toed shoe that offers a fascinating perspective on functional footwear. Go to peluva.com/DRSTEPHANIE to get 10% off your entire order.

This episode is packed with knowledge and inspiration, so be sure to share it with anyone eager to enhance their chances of living a vibrant and healthy life at 70 and beyond.


Mark Sisson is the founder of Primal Nutrition, LLC, and Primal Kitchen, LLC, and the extensive product offerings from Primal Blueprint. Mark is the author of numerous books, including The Primal Blueprint, which was credited with turbocharging the growth of the primal/paleo movement back in 2009. In 2017, he officially became a New York Times bestselling author with The Keto Reset Diet, which reached the #1 overall bestseller among all books on amazon.com for two days. Mark has written several other books, including popular Primal-themed cookbooks and lifestyle books. He is the publisher of MarksDailyApple.com, the #1-ranked blog for over a decade in its health and fitness category.

Resources mentioned:

Peluva shoes – https://peluva.com/
Facts About Falls – https://www.cdc.gov/falls/facts.html
Primal Health Coach Institute – https://www.primalhealthcoach.com

Connect with Mark on:

Website: https://www.marksdailyapple.com
IG: https://www.instagram.com/marksissonprimal/
YouTube: https://www.youtube.com/c/marksdailyapple
Facebook: https://www.facebook.com/marksdailyapple/
Twitter: https://twitter.com/Mark_Sisson

Episode Overview:

0:00:00 Intro
0:03:40 Welcome to the Show
0:08:01 The Acceptable Foods List for Longevity and Health
0:09:16 Importance of Avoiding Sugars and Industrial Seed Oils
0:12:46 The Role of Ketogenic Diet in Improving Insulin Sensitivity
0:16:43 Developing Metabolic Machinery to Burn Fats Efficiently
0:20:19 Metabolic Flexibility: Embracing Food Variety without Consequences
0:21:46 The Importance of Metabolic and Cognitive Flexibility
0:26:50 Muscle Mass and Longevity
0:31:15 The Demands of Building Muscle on the Body’s Organs
0:36:00 The Benefits of Resistance Training for Menopause Symptoms
0:39:10 The Importance of Recovery and Dedicated Stretching
0:42:18 Recommended Time for Gym Workouts: 35-45 Minutes
0:45:38 The Importance of Proper Biomechanics in Exercises
0:49:30 The Negative Impact of Encasing Feet in Shoes
0:53:27 Peluva Shoes: Comfort, Function, and Style
0:57:29 The Problem with Thick, Cushioned Shoes
1:00:39 The Transition to Midfoot Striking and Peluvas
1:06:45 The Importance of Foot Health and Fitness
1:15:04 Mark’s Daily Apple and Mark Sisson Primal on Instagram

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